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It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions appropriate to the circumstances of the individual, in consultation with them and their families and carers or guardian. When exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or the people using their service. Recommendations This guideline includes new and updated recommendations on:.

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Please take this quick survey to tell us about what happens after you publish a paper. Hereditary Cancer in Clinical Practice. DecemberCite as.

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Breast cancer is amongst frequently diagnosed cancer type throughout the world. Due to reduced efficacy of current chemotherapeutics, several natural products have been screened for better alternatives. The cytotoxic activity of fractions prepared from leaves extract of Vitex rotundifolia V. The active fractions induce apoptosis in MCF-7 cell line determined by annexin V base assay.

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